From listmaster animalgenome.org Wed Jul 17 08:33:39 2019
Return-Path: <listmasteranimalgenome.org>
From: "Dong Xia" <dxiarvc.ac.uk>
Postmaster: submission approved by list moderator
To: Members of AnGenMap <angenmapanimalgenome.org>
Subject: Frontiers in Genetics Research Topic
Date: Wed, 17 Jul 2019 08:33:39 -0500
Please join us to make an excellent contribution to this exciting
topic:
Genetics Architecture and Underlying Molecular Mechanisms in Host-
Pathogen Interactions
https://www.frontiersin.org/...search-topics/10855/
Dynamic host-pathogen interactions determine the outcome of
infections, clinical sequelae and the success of prophylactic or
therapeutic treatments. The use of a wide variety of molecular and
cell biology tools such as advanced microscopy, -omics techniques, as
well as data analysis capacities facilitated by advanced statistical
and machine learning algorithms have increased our understanding in
host-pathogen interactions. However, the explicit underlying
molecular mechanisms remain elusive or unexplored. This has
restrained the development of novel disease intervention strategies.
The identification of host genes and key pathogen-interacting factors
by a genome-wide genetic expression, epigenetic profiling, and other
emerging technologies as well as the dissection of the role of
microbiome composition should provide important insights to combating
infectious diseases.
This Research Topic aims to present state-of-the-art research and
future directions for host-pathogen interactions. Specifically, we
encourage the submission of reviews, original research, and method
articles, as well as perspective articles, in the following (but not
limited to) topics:
• Host genetic variation (structural variants, CNVs, and SNPs) that
conditions the outcome of pathogen (such as virus, bacteria, etc.)
infections
• Host functional genomics studies (transcriptomic, proteomic,
epigenetic, etc.) that shed light into the mechanisms shaping
infection processes
• Host microbiome composition and its effect on the pathogen load
• Systems biology approaches integrating the “omics” of infection and
host responses
• Utilization of cellular systems, animal models, or single cell
analyses to interrogate host genetic control of pathogenesis
• Genetic factors that control innate and adaptive immune responses
to pathogens
• Genetic and epigenetic factors that affect host immune response to
vaccine and treatments
Kind regards,
Topic Editor team
|
