Program in Comparative Genomics, Food Animal Biotechnology Center, Department ofVeterinary PathoBiology, University of Minnesota, St. Paul, Minnesota 55108,USA.
Title:
Interval mapping of growth in divergent swine cross.
A genomic scan of 18 swine autosomal chromosomes was constructed with 119polymorphic microsatellite (ms) markers to identify quantitative trait loci(QTL) for 11 growth traits in the University of Illinois Meishan x YorkshireSwine Resource Family. A significant QTL effect was found for post-weaningaverage daily gain (ADG) between 5.5 and 56 kg of body weight that mappedbetween markers SW373 and SW1301 near the telomere of Chromosome (Chr) 1 q(SSC1). This QTL effect had a nominal (pointwise) p-value of 0.000007, a genomewide p-value of 0.012, and accounted for 26% of the F2 phenotypic variance. Thesame chromosome region also had significant effects on ADG between birth and 56kg body weight (p-value =. 000227), and on ADG between 35 and 56 kg (p-value=.00077). These observations suggest that a significant QTL for post-weaninggrowth resides on SSC1.
