A. Stratil, M. Van Poucke, H. Bartenschlager, A. Knoll, M. Yerle, L. J. Peelman, M. Kopecny
Affiliation:
Academy of Sciences of the Czech Republic, Libechov, Czech Republic; Ghent University, Heidestraat, Belgium, University of Hohenheim, Stuttgart, Germany; Mendel university og Agriculture and Forestry, Zemedelska, Czech Republic; Labo
Title:
Porcine OGN and ASPN: mapping, polymorphisms and use for quantitative trait loci identification for growth and carcass traits in a Meishan x Pietrain intercross
The porcine orthologues of human chromosome HSA9q22.31 genes osteoglycin (OGN) and asporin (ASPN) were mapped to porcine chromosome SSC3 using linkage analysis and a somatic cell hybrid panel. This mapping was refined to SSC3q11 using fluorescence in situ hybridization. These results confirm the existence of a small conserved synteny group between SSC3 and HSA9. Polymorphisms were revealed in both genes, including a pentanucleotide microsatellite (SCZ003) in OGN and two single nucleotide polymorphisms (AM181682.1:g.780G>T and AM181682.1:g.825T>C) in ASPN. The two genes were included in a set of markers for quantitative trait loci (QTL) mapping on SSC3 in the
Hohenheim Meishan · Pie´train F2 family. Major QTL for growth and carcass traits were centred in the ASPN–SW902 region.
