Whole genome analysis for QTL/association enrichment
Running...
Version: Enrich S: beta v0.8
Data:
Number of disease susceptibility traits:
28
Number of QTL / associations found:
660
Number of chromosomes where QTL / associations are found:
19
Chi-squared (χ2) test: are disease susceptibility traits over-represented on some chromosomes?
Chromosomes
Total χ2
df
p-values
FDR *
Size of χ2
Chromosome X
712.78312
18
1.098607e-139
1.043677e-138
Chromosome 1
111.03764
18
2.016474e-15
2.554200e-15
Chromosome 2
2.43152
18
0.9999946
9.999946e-01
Chromosome 3
313.99508
18
6.324357e-56
2.002713e-55
Chromosome 4
2461.72248
18
9e-41
1.710000e-40
Chromosome 5
253.58312
18
1.521915e-43
3.614548e-43
Chromosome 6
36.58312
18
0.005935943
7.048932e-03
Chromosome 7
4.12860
18
0.9997017
9.999946e-01
Chromosome 8
175.05572
18
9.117503e-28
1.237375e-27
Chromosome 9
225.79508
18
6.558228e-38
1.038386e-37
Chromosome 10
346.61956
18
1.142831e-62
5.428447e-62
Chromosome 11
282.98312
18
1.501083e-49
4.074368e-49
Chromosome 12
225.79508
18
6.558228e-38
1.038386e-37
Chromosome 13
18200.05572
18
9e-41
1.710000e-40
Chromosome 14
0.05572
18
0.998329325823115
9.999946e-01
Chromosome 15
738.23764
18
4.315507e-145
8.199463e-144
Chromosome 16
665.64988
18
1.093214e-129
6.923689e-129
Chromosome 17
175.05572
18
9.117503e-28
1.237375e-27
Chromosome 18
313.99508
18
6.324357e-56
2.002713e-55
Chi-squared (χ2) test: Which of the 28 disease susceptibility traits are over-represented in the QTLdb
Traits
Total χ2
df
p-values
FDR *
Size of χ2
ADV antibody titer
19.78572
27
0.839627
9.042137e-01
Actinobacillus pleuropneumoniae susceptibility
312.71541
27
2.108612e-50
5.904114e-49
Anti-K88 E.coli IgG levels
37.82351
27
0.08069273
1.737997e-01
Anti-O149 E.coli IgG level response
22.57141
27
0.7078085
8.616799e-01
Anti-O149 E.coli IgG levels
22.57141
27
0.7078085
8.616799e-01
Antibody response to Brucella suis
75.01428
27
2.101116e-06
1.176625e-05
Brucellosis susceptibility
26.69368
27
0.480412
7.473076e-01
CSFV antibody level
33.74684
27
0.1735305
3.239236e-01
Change in Mycoplasma hyopneumoniae antibody titer
42.03844
27
0.03262923
7.613487e-02
Change in tetanus antibody titer
42.99998
27
0.02615917
6.658698e-02
Chronic pleuritis
20.01523
27
0.8301164
9.042137e-01
Enterotoxigenic E. coli susceptibility
309.79918
27
8.067432e-50
1.129440e-48
Leptospirosus susceptibility
21.64186
27
0.7553463
8.812374e-01
Melanoma susceptibility
62.23396
27
0.0001334088
4.669308e-04
Mycoplasma hyopneumoniae antibody titer
28.47193
27
0.3869598
6.771797e-01
Mycoplasmal pneumonia susceptibility
64.94195
27
5.727576e-05
2.291030e-04
PRRS viral load
66.59999
27
3.379981e-05
1.577324e-04
PRRSV antibody titer
136.98346
27
1.128805e-16
7.901635e-16
PRRSV susceptibility
60.68841
27
0.0002141475
6.662367e-04
Periweaning failure to thrive syndrome
195.9261
27
1.475344e-27
1.376988e-26
Postpartum dysgalactia syndrome susceptibility
16.28379
27
0.9473204
9.808600e-01
Pseudorabies susceptibility
26.92769
27
0.4677015
7.473076e-01
Pseudorabies virus antibody titer
14.04012
27
0.98086
9.808600e-01
Sarcocystis miescheriana IgG levels
43.8915
27
0.02121763
5.940936e-02
Sarcocystis miescheriana IgM levels
23.35259
27
0.6659331
8.616799e-01
Small intestinal Escherichia coli F18 receptor
22.57141
27
0.7078085
8.616799e-01
Tetanus antibody titer
24.11666
27
0.6238373
8.616799e-01
Tuberculosis susceptibility
36.72904
27
0.1002372
2.004744e-01
Correlations found between some of these traits for your reference
No correlation data found on these traits
Overall Test
Data
Chi'Square Test
Fisher's Exact Test
Number of chrom.:
19
χ2
=
25245.563000
Number of traits:
28
df
=
486
Number of QTLs:
660
p-value
=
0
FOOT NOTE: * : FDR is short for "false
discovery rate", representing the expected proportion of type I errors. A type I
error is where you incorrectly reject the null hypothesis, i.e. you get a false
positive. It's statistical definition is FDR = E(V/R | R > 0) P(R > 0), where
V = Number of Type I errors (false positives); R = Number of rejected hypotheses.
Benjamini–Hochberg procedure is a practical way to estimate FDR.
Running...
