Pig QTL Database

Release 56
(Apr 24, 2025)

. . . from browsing trait ontology

References

On trait: Offspring number

An SM, Hwang JH, Kwon S, Yu GE, Park DH, Kang DG, Kim TW, Park HC, Ha J, Kim CW (2018). Effect of Single Nucleotide Polymorphisms in IGFBP2 and IGFBP3 Genes on Litter Size Traits in Berkshire Pigs Animal biotechnology,29(4):301-308. [see all QTL by this paper]
B. Buske, C. Brunsch, K. Zeller, P. Reinecke, G. Brockmann (2005). Analysis of properdin (BF) genotpyes associated with litter size in a commercial pig cross population J Anim Breed Genet,122: 259-263. [see all QTL by this paper]
B. Buske, I. Sternstein, M. Reißmann & G. Brockmann (2006). Detection of novel single-nucleotide polymorphisms (SNPs) in the CYP21 gene and association analysis of two SNPs for CYP21 and ESR2 with litter size in a commercial sow population. J Anim Breed Genet,123(5):343-8. [see all QTL by this paper]
Balcells I, Castello A, Mercade A, Noguera JL, Fernandez-Rodriguez A, Sanchez A, Tomas A (2011). Analysis of porcine MUC4 gene as a candidate gene for prolificacy QTL on SSC13 in an Iberian x Meishan F2 population. BMC genetics,12: 93. [see all QTL by this paper]
Balcells I, Castello A, Noguera JL, Fernandez-Rodriguez A, Sanchez A, Tomas A (2011). Sequencing and gene expression of the porcine ITIH SSC13 cluster and its effect on litter size in an Iberian x Meishan F2 population. Animal reproduction science,128(1-4): 85-92. [see all QTL by this paper]
Bergfelder-Drüing S, Grosse-Brinkhaus C, Lind B, Erbe M, Schellander K, Simianer H, Tholen E (2015). A genome-wide association study in large white and landrace pig populations for number piglets born alive PloS one,10(3): e0117468. [see all QTL by this paper]
Bjerre D, Madsen L B, Mark T, Cirera S, Larsen K, Jørgensen C B, Fredholm M (2013). Potential role of the porcine superoxide dismutase 1 (SOD1) gene in pig reproduction Animal biotechnology,24(1): 1-9. [see all QTL by this paper]
Brinke I, GroÃŸe-Brinkhaus C, Roth K, PrÃ¶ll-Cornelissen MJ, Henne H, Schellander K, Tholen E (2021). Genomic background and genetic relationships between boar taint and fertility traits in German Landrace and Large White BMC genetics,21(1): 61. [see all QTL by this paper]
Cassady JP, Johnson RK, Pomp D, Rohrer GA, Van Vleck LD, Spiegel EK, Gilson KM. (2001). Identification of quantitative trait loci affecting reproduction in pigs. J Anim Sci,Mar;79(3):623-33.. [see all QTL by this paper]
Chen C Y, Guo Y M, Zhang Z Y, Ren J, Huang L S (2010). A whole genome scan to detect quantitative trait loci for gestation length and sow maternal ability related traits in a White Duroc × Erhualian F2 resource population. Animal : an international journal of animal bioscience,4 (6): 861-6. [see all QTL by this paper]
Chen J, Wu Z, Chen R, Huang Z, Han X, Qiao R, Wang K, Yang F, Li XJ, Li XL (2022). Identification of Genomic Regions and Candidate Genes for Litter Traits in French Large White Pigs Using Genome-Wide Association Studies Animals : an open access journal from MDPI,12(12):1584. [see all QTL by this paper]
Chen Z, Ye S, Teng J, Diao S, Yuan X, Chen Z, Zhang H, Li J, Zhang Z (2019). Genome-wide association studies for the number of animals born alive and dead in duroc pigs Theriogenology,139: 36-42. [see all QTL by this paper]
Coster A, Madsen O, Heuven HC, Dibbits B, Groenen MA, van Arendonk JA, Bovenhuis H (2012). The imprinted gene DIO3 is a candidate gene for litter size in pigs. PloS one,7(2): e31825. [see all QTL by this paper]
E Sell-Kubiak, N Duijvesteijn, M S Lopes, L L G Janss, E F Knol, P Bijma, H A Mulder (2015). Genome-wide association study reveals novel loci for litter size and its variability in a Large White pig population BMC Genomics,16. [see all QTL by this paper]
Fernandez-Rodriguez, A: Rodriguez, C; Varona, L; Balcells, I; Noguera, J L; Ovilo, C; Fernandez, A I (2009). Analysis of candidate genes underlying two epistatic quantitative trait loci on SSC12 affecting litter size in pig. Animal genetics,41(1):73-80. [see all QTL by this paper]
Fu Y, Fu J, Wang A (2012). Association of EphA4 polymorphism with swine reproductive traits and mRNA expression of EphA4 during embryo implantation Mol Biol Rep,39(3):2689-96. [see all QTL by this paper]
Gunawan A, Cinar M, Uddin M, Kaewmala K, Tesfaye D, Phatsara C, Tholen E, Looft C, Schellander K (2012). Investigation on Association and Expression of ESR2 as a Candidate Gene for Boar Sperm Quality and Fertility Reprod Domest Anim,47(5):782-90. [see all QTL by this paper]
Guo X, Su G, Christensen OF, Janss L, Lund MS (2016). Genome-wide association analyses using a Bayesian approach for litter size and piglet mortality in Danish Landrace and Yorkshire pigs BMC genomics,17(1): 468. [see all QTL by this paper]
HÃ¤ggman J, Uimari P, (2017). Novel harmful recessive haplotypes for reproductive traits in pigs Journal of animal breeding and genetics,134(2): 129-135. [see all QTL by this paper]
He L C, Li P H, Ma X, Sui S P, Gao S, Kim S W, Gu Y Q, Huang Y, Ding N S, Huang R H (2017). Identification of new single nucleotide polymorphisms affecting total number born and candidate genes related to ovulation rate in Chinese Erhualian pigs Animal genetics,48(1):48-54. [see all QTL by this paper]
He Y, Zhou X, Zheng R, Jiang Y, Yao Z, Wang X, Zhang Z, Zhang H, Li J, Yuan X (2021). The Association of an SNP in the EXOC4 Gene and Reproductive Traits Suggests Its Use as a Breeding Marker in Pigs Animals : an open access journal from MDPI,11(2). [see all QTL by this paper]
Hernandez S C, Finlayson H A, Ashworth C J, Haley C S, Archibald A L (2014). A genome-wide linkage analysis for reproductive traits in F2 Large White × Meishan cross gilts Animal genetics,45(2):191-7. [see all QTL by this paper]
Holl, J W; Cassady, J P; Pomp, D; Johnson, R K (2004). A genome scan for quantitative trait loci and imprinted regions affecting reproduction in pigs. J Anim Sci,82 (12): 3421-9. [see all QTL by this paper]
Hong Y, Tan C, He X, Wu D, Zhang Y, Song C, Wu Z (2024). Genome-Wide Association Study of Reproductive Traits in Large White Pigs Animals : an open access journal from MDPI,14(19):2874. [see all QTL by this paper]
Horogh, G; Zsolnai, A; Komiosi, I; Nyiri, A; Anton, I; Fesus, L (2005). Oestrogen receptor genotypes and litter size in Hungarian Large White pigs. Journal of animal breeding and genetics,122 (1): 56-61. [see all QTL by this paper]
Jiang Y, Tang S, Xiao W, Yun P, Ding X (2020). A genome-wide association study of reproduction traits in four pig populations with different genetic backgrounds Asian-Australasian journal of animal sciences,33(9):1400-1410. [see all QTL by this paper]
Jiugang Z, Jing L, Yonggang L (2012). Characterization, expression profile, polymorphism and association of porcine NAT9 gene Mol Biol Rep,39(3):3137-42. [see all QTL by this paper]
King AH, Jiang Z, Gibson JP, Haley CS, Archibald AL. (2003). Mapping quantitative trait loci affecting female reproductive traits on porcinechromosome 8. Biol Reprod.,Jun;68(6):2172-9. Epub 2003 Jan 22.. [see all QTL by this paper]
Laliotis G P, Marantidis A, Avdi M (2016). Association of BF, RBP4, and ESR2 Genotypes with Litter Size in an Autochthonous Pig Population Animal biotechnology,: 1-6. [see all QTL by this paper]
Lan J, Zhao J, Liu Y (2012). Molecular cloning, sequence characterization, polymorphism and association analysis of porcine ROPN1 gene Mol Biol Rep,39(3):2739-43. [see all QTL by this paper]
Lan Q, Deng Q, Qi S, Zhang Y, Li Z, Yin S, Li Y, Tan H, Wu M, Yin Y, He J, Liu M (2023). Genome-Wide Association Analysis Identified Variants Associated with Body Measurement and Reproduction Traits in Shaziling Pigs Genes,14(2):522. [see all QTL by this paper]
Lee J, Kang JH, Kim JM (2019). Bayes Factor-Based Regulatory Gene Network Analysis of Genome-Wide Association Study of Economic Traits in a Purebred Swine Population Genes,10(4). [see all QTL by this paper]
Lei B, Gao S, Luo LF, Xia XY, Jiang SW, Deng CY, Xiong YZ, Li FE (2011). A SNP in the miR-27a gene is associated with litter size in pigs. Molecular biology reports,38(6): 3725-9. [see all QTL by this paper]
Li M, Li X, Liu C, Han J, Han X, Wang K, Qiao R, Yang F, Li XL, Li XJ (2023). Genome-wide association study reveals the candidate genes for reproduction traits in Yunong black pigs Animal Genetics,54(3):403-407. [see all QTL by this paper]
Li X, Ye J, Han X, Qiao R, Li X, Lv G, Wang K (2019). Whole-genome sequencing identifies potential candidate genes for reproductive traits in pigs Genomics,S0888-7543(18)30673-6. [see all QTL by this paper]
Li, K; Ren, J; Xing, Y; Zhang, Z; Ma, J; Guo, Y; Huang, L (2009). Quantitative trait loci for litter size and prenatal loss in a White Duroc x Chinese Erhualian resource population Animal genetics,40(6):963-6. [see all QTL by this paper]
Liu R, Deng D, Liu X, Xiao Y, Huang J, Wang F, Li X, Yu M (2019). A miR-18a binding-site polymorphism in CDC42 3'UTR affects CDC42 mRNA expression in placentas and is associated with litter size in pigs Mammalian genome : official journal of the International Mammalian Genome Society,30(1-2): 34-41. [see all QTL by this paper]
Ma X, Li P H, Zhu M X, He L C, Sui S P, Gao S, Su G S, Ding N S, Huang Y, Lu Z Q, Huang X G, Huang R H (2018). Genome-wide association analysis reveals genomic regions on Chromosome 13 affecting litter size and candidate genes for uterine horn length in Erhualian pigs Animal : an international journal of animal bioscience,12(12):2453-2461. [see all QTL by this paper]
Marantidis A, Papadopoulos A I, Michailidis G, Avdi M (2013). Association of BF gene polymorphism with litter size in a commercial pig cross population Animal reproduction science,141(1-2): 75-9. [see all QTL by this paper]
Mucha A, Ropka-Molik K, Piórkowska K, Tyra M, Oczkowicz M (2013). Effect of EGF, AREG and LIF genes polymorphisms on reproductive traits in pigs Animal reproduction science,137(1-2): 88-92. [see all QTL by this paper]
Munoz M, Fernandez AI, Ovilo C, Munoz G, Rodriguez C, Fernandez A, Alves E, Silio L (2010). Non-additive effects of RBP4, ESR1 and IGF2 polymorphisms on litter size at different parities in a Chinese-European porcine line Genet Sel Evol,42:23. [see all QTL by this paper]
Onteru SK, Fan B, Du ZQ, Garrick DJ, Stalder KJ, Rothschild MF (2012). A whole-genome association study for pig reproductive traits. Animal genetics,43(1): 18-26. [see all QTL by this paper]
Onteru SK, Fan B, Nikkilä MT, Garrick DJ, Stalder KJ, Rothschild MF (2011). Whole-genome association analyses for lifetime reproductive traits in the pig. Journal of animal science,89(4): 988-95. [see all QTL by this paper]
Ran XQ, Pan H, Huang SH, Liu C, Niu X, Li S, Wang JF (2018). Copy number variations of MTHFSD gene across pig breeds and its association with litter size traits in Chinese indigenous Xiang pig Journal of animal physiology and animal nutrition,102(5). [see all QTL by this paper]
Rothschild M, Jacobson C, Vaske D, Tuggle C, Wang L, Short T, Eckardt G, Sasaki S, Vincent A, McLaren D, Southwood O, van der Steen H, Mileham A, Plastow G. (1996). The estrogen receptor locus is associated with a major gene influencing littersize in pigs. Proc Natl Acad Sci U S A.,Jan 9;93(1):201-5.. [see all QTL by this paper]
Schneider J F, Miles J R, Brown-Brandl T M, Nienaber J A, Rohrer G A, Vallet J L (2015). Genomewide association analysis for average birth interval and stillbirth in swine Journal of animal science,93(2): 529-40. [see all QTL by this paper]
Schneider J F, Rempel L A, Snelling W M, Wiedmann R T, Nonneman D J, Rohrer G A, (2012). Genome-wide association study of swine farrowing traits. Part II: Bayesian analysis of marker data. Journal of animal science,90 (10): 3360-7. [see all QTL by this paper]
Shi L, Li H, Gao X, Wang L (2022). Genome-wide association study of three litter traits in Yorkshire pigs Animal Genetics,53(4): 510-512. [see all QTL by this paper]
Shifei P, Yonggang L (2012). Molecular characterization, polymorphism and association of porcine IBP4 gene. Folia biologica,58 (1): 30-6. [see all QTL by this paper]
Sironen A, Uimari P, Iso-Touru T, Vilkki J (2012). L1 insertion within SPEF2 gene is associated with increased litter size in the Finnish Yorkshire population. Journal of animal breeding and genetics,129 (2): 92-7. [see all QTL by this paper]
Stafuzza NB, Silva RMO, Fragomeni BO, Masuda Y, Huang Y, Gray K, Lourenco DAL (2019). A genome-wide single nucleotide polymorphism and copy number variation analysis for number of piglets born alive BMC genomics,20(1): 321. [see all QTL by this paper]
Stinckens, A; Mathur, P; Janssens, S; Bruggeman, V; Onagbesan, O M; Schroyen, M; Spincemaille, G; Decuypere, E; Georges, M; Buys (2010). Indirect effect of IGF2 intron3 g.3072G>A mutation on prolificacy in sows. Animal genetics,41(5):493-8. [see all QTL by this paper]
Sun H, Cheng Y, He Y, Cheng C, Zhao H, Yang S, Wei M, Yang J, Liang S, Bai C, Sun B (2024). Genome-wide association studies for the number of piglets born alive and dead in Dongliao black pigs Animal Genetics,55(2): 282-285. [see all QTL by this paper]
Sun J, Wang C, Wu Y, Xiang J, Zhang Y (2024). Association Analysis of METTL23 Gene Polymorphisms with Reproductive Traits in Kele Pigs Genes,15(8):1061. [see all QTL by this paper]
Sun J, Xiao J, Jiang Y, Wang Y, Cao M, Wei J, Yu T, Ding X, Yang G (2023). Genome-Wide Association Study on Reproductive Traits Using Imputation-Based Whole-Genome Sequence Data in Yorkshire Pigs Genes,14(4):861. [see all QTL by this paper]
Suwannasing R, Duangjinda M, Boonkum W, Taharnklaew R, Tuangsithtanon K (2018). The identification of novel regions for reproduction trait in Landrace and Large White pigs using a single step genome-wide association study Asian-Australasian journal of animal sciences,31(12): 1852-1862. [see all QTL by this paper]
Tao H, Mei S, Sun X, Peng X, Zhang X, Ma C, Wang L, Hua L, Li F (2013). Associations of TCF12, CTNNAL1 and WNT10B gene polymorphisms with litter size in pigs Animal reproduction science,140(3-4): 189-94. [see all QTL by this paper]
Tremoen NH, Van Son M, Andersen-Ranberg I, Grindflek E, Myromslien FD, Gaustad AH, VÃ¥ge DI (2020). Association between single-nucleotide polymorphisms within candidate genes and fertility in Landrace and Duroc pigs Acta veterinaria Scandinavica,61(1): 58. [see all QTL by this paper]
Trenhaile M, Petersen J, Kachman S, Johnson R, Ciobanu D (2016). Long-term selection for litter size in swine results in shifts in allelic frequency in regions involved in reproductive processes Animal Genetics,. [see all QTL by this paper]
Tribout, T; Iannuccelli, N; Druet, T; Gilbert, H; Riquet, J; Gueblez, R; Mercat, M; Bidanel, J P; Milan, D; Le Roy, P (2008). Detection of quantitative trait loci for reproduction and production traits in Large White and French Landrace pig populations. Genetics, Selection, Evolution : GSE,40 (1): 61-78. [see all QTL by this paper]
Uimari P, Sironen A, Sevón-Aimonen ML (2011). Whole-genome SNP association analysis of reproduction traits in the Finnish Landrace pig breed. Genetics, Selection, Evolution : GSE,43: 42. [see all QTL by this paper]
Verardo LL, Silva FF, Lopes MS, Madsen O, Bastiaansen JWM, Knol EF, Kelly M, Varona L, Lopes PS, Guimarães SEF (2016). Revealing new candidate genes for reproductive traits in pigs: combining Bayesian GWAS and functional pathways Genetics, Selection, Evolution : GSE,48(1): 9. [see all QTL by this paper]
Wang H, Wu S, Wu J, Sun S, Wu S, Bao W (2018). Association analysis of the SNP (rs345476947) in the FUT2 gene with the production and reproductive traits in pigs Genes & genomics,40(2): 199-206. [see all QTL by this paper]
Wang X, Wang L, Shi L, Zhang P, Li Y, Li M, Tian J, Wang L, Zhao F (2022). GWAS of Reproductive Traits in Large White Pigs on Chip and Imputed Whole-Genome Sequencing Data International journal of molecular sciences,23(21):13338. [see all QTL by this paper]
Wang Y, Ding X, Tan Z, Xing K, Yang T, Wang Y, Sun D, Wang C (2018). Genome-wide association study for reproductive traits in a Large White pig population Animal genetics,49(2):127-131. [see all QTL by this paper]
Wang Y, Zhang T, Wang C (2020). Detection and analysis of genome-wide copy number variation in the pig genome using an 80K SNP Beadchip Journal of animal breeding and genetics,137(2):166-176. [see all QTL by this paper]
Wijesena HR, Kachman SD, Lents CA, Riethoven JJ, Trenhaile-Grannemann MD, Safranski TJ, Spangler ML, Ciobanu DC (2021). Fine mapping genetic variants associated with age at puberty and sow fertility using SowPro90 genotyping array Journal of animal science,98(10). [see all QTL by this paper]
Wilkie PJ, Paszek AA, Beattie CW, Alexander LJ, Wheeler MB, Schook LB. (1999). A genomic scan of porcine reproductive traits reveals possible quantitative trait loci (QTLs) for number of corpora lutea. Mammalian genome,Jun;10(6):573-8.. [see all QTL by this paper]
Wu P, Yang Q, Wang K, Zhou J, Ma J, Tang Q, Jin L, Xiao W, Jiang A, Jiang Y, Zhu L, Li X, Tang G (2018). Single step genome-wide association studies based on genotyping by sequence data reveals novel loci for the litter traits of domestic pigs Genomics,110(3):171-179. [see all QTL by this paper]
Xu Z, Lin Q, Cai X, Zhong Z, Teng J, Li B, Zeng H, Gao Y, Cai Z, Wang X, Shi L, Wang X, Wang Y, Zhang Z, Lin Y, Liu S, Yin H, Bai Z, Wei C, Zhou J, Zhang W, Zhang X, Shi S, Wu J, Diao S, Liu Y, Pan X, Feng X, Liu R, Su Z, Chang C, Zhu Q, Wu Y, The PigGTEx Consortium, Zhou Z, Bai L, Li K, Wang Q, Pan Y, Xu Zhong, Peng X, Mei S, Mo D, Liu X, Zhang H, Yuan X, Liu Y, Liu G, Su G, Sahana G, Lund MS, Ma L, Xiang R, Shen X, Li P, Huang R, Ballester M, Piazuelo DC, Amills M, Clop A, Mortensen PK, Fredholm M, Tang G, Li M, Li X, Ding X, Li J, Chen Y, Zhang Q, Zhao Y, Zhao F, Fang L, Zhang Z (2024). Integrating large-scale meta-GWAS and PigGTEx resources to decipher the genetic basis of 232 complex traits in pigs. bioRxiv,. [see all QTL by this paper]
Yonggang L, Xueshan X (2012). Molecular characterization, tissue expression, polymorphism and association of porcine LCK gene Mol Biol Rep,39(4):4023-8. [see all QTL by this paper]
Zhang L, Zhang S, Yuan M, Zhan F, Song M, Shang P, Yang F, Li X, Qiao R, Han X, Li X, Fang M, Wang K (2023). Genome-Wide Association Studies and Runs of Homozygosity to Identify Reproduction-Related Genes in Yorkshire Pig Population Genes,14(12):2133. [see all QTL by this paper]
Zhang Q, Huang R, Ma X, Jiang N, Zhou W, Gao C, Zhao M, Niu P, Zhang Z, Li Q, Zhou J, Li P (2020). Association of Rs339939442 in the AHR Gene with Litter Size are Inconsistent among Chinese Indigenous Pigs and Western Commercial Pigs. Animals : an open access journal from MDPI,10(1):E11. [see all QTL by this paper]
Zhang Y, Lai J, Wang X, Li M, Zhang Y, Ji C, Chen Q, Lu S (2023). Genome-wide single nucleotide polymorphism (SNP) data reveal potential candidate genes for litter traits in a Yorkshire pig population Archives animal breeding,66: 357-368. [see all QTL by this paper]
Zhang Z, Chen Z, Ye S, He Y, Huang S, Yuan X, Chen Z, Zhang H, Li J (2019). Genome-Wide Association Study for Reproductive Traits in a Duroc Pig Population Animals : an open access journal from MDPI,9(10). [see all QTL by this paper]
Zhao YX, Gao GX, Zhou Y, Guo CX, Li B, El-Ashram S, Li ZL (2022). Genome-wide association studies uncover genes associated with litter traits in the pig Animal : an international journal of animal bioscience,16(12): 100672. [see all QTL by this paper]
Zheng X, Zhao P, Yang K, Ning C, Wang H, Zhou L, Liu J (2020). CNV analysis of Meishan pig by next-generation sequencing and effects of AHR gene CNV on pig reproductive traits Journal of animal science and biotechnology,11: 42. [see all QTL by this paper]

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