Whole genome analysis for QTL/association enrichment
Running...
Version: Enrich S: beta v0.8
Data:
Number of congenital defects traits:
5
Number of QTL / associations found:
115
Number of chromosomes where QTL / associations are found:
20
Chi-squared (χ2) test: are congenital defects traits over-represented on some chromosomes?
Chromosomes
Total χ2
df
p-values
FDR *
Size of χ2
Chromosome X
6.57610
19
0.9961538
9.983293e-01
Chromosome 1
0.05435
19
0.998329325823115
9.983293e-01
Chromosome 2
0.05435
19
0.998329325823115
9.983293e-01
Chromosome 3
33.96740
19
0.01854101
1.236067e-01
Chromosome 4
6.57610
19
0.9961538
9.983293e-01
Chromosome 5
12.22825
19
0.8756384
9.983293e-01
Chromosome 6
6.57610
19
0.9961538
9.983293e-01
Chromosome 7
19.61955
19
0.4177892
9.983293e-01
Chromosome 8
12.22825
19
0.8756384
9.983293e-01
Chromosome 9
12.22825
19
0.8756384
9.983293e-01
Chromosome 12
12.22825
19
0.8756384
9.983293e-01
Chromosome 13
23.96740
19
0.1974058
9.870290e-01
Chromosome 15
795.70650
19
1.757582e-156
3.515164e-155
Chromosome 16
12.22825
19
0.8756384
9.983293e-01
Chromosome 17
6.57610
19
0.9961538
9.983293e-01
Chromosome 19
45.70650
19
0.0005453098
5.453098e-03
Chromosome 22
19.61955
19
0.4177892
9.983293e-01
Chromosome 23
19.61955
19
0.4177892
9.983293e-01
Chromosome 24
6.57610
19
0.9961538
9.983293e-01
Chromosome 26
6.57610
19
0.9961538
9.983293e-01
Chi-squared (χ2) test: Which of the 5 congenital defects traits are over-represented in the QTLdb
Traits
Total χ2
df
p-values
FDR *
Size of χ2
Entropion
5.56444
4
0.2341230
2.341230e-01
Heritable cataract
37.33334
4
1.537797e-07
1.922246e-07
Inherited Ovine Arthrogryposis
56.50001
4
1.575087e-11
2.625145e-11
Microphthalmia
114.00001
4
1.020094e-23
5.100470e-23
Microtia
57.88888
4
8.052034e-12
2.013008e-11
Correlations found between some of these traits for your reference
No correlation data found on these traits
Overall Test
Data
Chi'Square Test
Fisher's Exact Test
Number of chrom.:
20
χ2
=
1058.913000
Number of traits:
5
df
=
76
Number of QTLs:
115
p-value
=
5.4243e-173
FOOT NOTE: * : FDR is short for "false
discovery rate", representing the expected proportion of type I errors. A type I
error is where you incorrectly reject the null hypothesis, i.e. you get a false
positive. It's statistical definition is FDR = E(V/R | R > 0) P(R > 0), where
V = Number of Type I errors (false positives); R = Number of rejected hypotheses.
Benjamini–Hochberg procedure is a practical way to estimate FDR.
Running...
