Whole genome analysis for QTL/association enrichment
Running...
Version: Enrich S: beta v0.8
Data:
Number of health-other traits:
12
Number of QTL / associations found:
94
Number of chromosomes where QTL / associations are found:
20
Chi-squared (χ2) test: are health-other traits over-represented on some chromosomes?
Chromosomes
Total χ2
df
p-values
FDR *
Size of χ2
Chromosome Z
0.22980
19
0.998329325823115
9.998100e-01
Chromosome 1
764.14464
19
8.901613e-150
1.780323e-148
Chromosome 2
47.20848
19
0.0003334456
3.334456e-03
Chromosome 3
13.50636
19
0.8116706
9.998100e-01
Chromosome 4
0.22980
19
0.998329325823115
9.998100e-01
Chromosome 5
7.37868
19
0.9919046
9.998100e-01
Chromosome 6
7.37868
19
0.9919046
9.998100e-01
Chromosome 8
4.31484
19
0.99981
9.998100e-01
Chromosome 10
0.22980
19
0.998329325823115
9.998100e-01
Chromosome 11
7.37868
19
0.9919046
9.998100e-01
Chromosome 12
34.95324
19
0.01414902
5.659608e-02
Chromosome 13
34.95324
19
0.01414902
5.659608e-02
Chromosome 14
7.37868
19
0.9919046
9.998100e-01
Chromosome 15
7.37868
19
0.9919046
9.998100e-01
Chromosome 16
4.31484
19
0.99981
9.998100e-01
Chromosome 18
18.61272
19
0.4819208
9.998100e-01
Chromosome 23
34.95324
19
0.01414902
5.659608e-02
Chromosome 26
1.25112
19
0.998329325823115
9.998100e-01
Chromosome 27
18.61272
19
0.4819208
9.998100e-01
Chromosome 28
7.37868
19
0.9919046
9.998100e-01
Chi-squared (χ2) test: Which of the 12 health-other traits are over-represented in the QTLdb
Traits
Total χ2
df
p-values
FDR *
Size of χ2
Altitude adaptation
37.28566
11
0.0001031951
6.191706e-04
Body temperature
21.51649
11
0.02839830
6.815592e-02
Early mortality
15.93941
11
0.1433952
1.911936e-01
Fluid in the heart sac
30.33331
11
0.001404364
4.213092e-03
Heat tolerance
53.39994
11
1.518333e-07
1.822000e-06
Late mortality
7.9697
11
0.7160155
7.429873e-01
Liver abnormalities
30.33331
11
0.001404364
4.213092e-03
Liver color
17.79997
11
0.08633958
1.480107e-01
Right ventricular weight as percentage of body weight
17.19255
11
0.1023076
1.534614e-01
Thymus weight
7.6647
11
0.7429873
7.429873e-01
Total mortality
17.79997
11
0.08633958
1.480107e-01
Total ventricular weight as percentage of body weight
9.44442
11
0.5809414
6.971297e-01
Correlations found between some of these traits for your reference
No correlation data found on these traits
Overall Test
Data
Chi'Square Test
Fisher's Exact Test
Number of chrom.:
20
χ2
=
1021.786920
Number of traits:
12
df
=
209
Number of QTLs:
94
p-value
=
3.374971e-107
FOOT NOTE: * : FDR is short for "false
discovery rate", representing the expected proportion of type I errors. A type I
error is where you incorrectly reject the null hypothesis, i.e. you get a false
positive. It's statistical definition is FDR = E(V/R | R > 0) P(R > 0), where
V = Number of Type I errors (false positives); R = Number of rejected hypotheses.
Benjamini–Hochberg procedure is a practical way to estimate FDR.