Release 56
(Apr 24, 2025)

Whole genome analysis for QTL/association enrichment

Running...
Version: Enrich S: beta v0.8
Search: to limit the list of your trait choices:
(optional) focus on chromosome with Mb windows across its length

Data:

Number of health-other traits:12
Number of QTL / associations found:94
Number of chromosomes where QTL / associations are found:20

Chi-squared (χ2) test: are health-other traits over-represented on some chromosomes?

Chromosomes Total χ2 df p-values FDR * Size of χ2
Chromosome Z0.22980190.9983293258231159.998100e-01
Chromosome 1764.14464198.901613e-1501.780323e-148
Chromosome 247.20848190.00033344563.334456e-03
Chromosome 313.50636190.81167069.998100e-01
Chromosome 40.22980190.9983293258231159.998100e-01
Chromosome 57.37868190.99190469.998100e-01
Chromosome 67.37868190.99190469.998100e-01
Chromosome 84.31484190.999819.998100e-01
Chromosome 100.22980190.9983293258231159.998100e-01
Chromosome 117.37868190.99190469.998100e-01
Chromosome 1234.95324190.014149025.659608e-02
Chromosome 1334.95324190.014149025.659608e-02
Chromosome 147.37868190.99190469.998100e-01
Chromosome 157.37868190.99190469.998100e-01
Chromosome 164.31484190.999819.998100e-01
Chromosome 1818.61272190.48192089.998100e-01
Chromosome 2334.95324190.014149025.659608e-02
Chromosome 261.25112190.9983293258231159.998100e-01
Chromosome 2718.61272190.48192089.998100e-01
Chromosome 287.37868190.99190469.998100e-01

Chi-squared (χ2) test: Which of the 12 health-other traits are over-represented in the QTLdb

Traits Total χ2 df p-values FDR * Size of χ2
Altitude adaptation 37.28566 11 0.0001031951 6.191706e-04
Body temperature 21.51649 11 0.02839830 6.815592e-02
Early mortality 15.93941 11 0.1433952 1.911936e-01
Fluid in the heart sac 30.33331 11 0.001404364 4.213092e-03
Heat tolerance 53.39994 11 1.518333e-07 1.822000e-06
Late mortality 7.9697 11 0.7160155 7.429873e-01
Liver abnormalities 30.33331 11 0.001404364 4.213092e-03
Liver color 17.79997 11 0.08633958 1.480107e-01
Right ventricular weight as percentage of body weight 17.19255 11 0.1023076 1.534614e-01
Thymus weight 7.6647 11 0.7429873 7.429873e-01
Total mortality 17.79997 11 0.08633958 1.480107e-01
Total ventricular weight as percentage of body weight 9.44442 11 0.5809414 6.971297e-01

Correlations found between some of these traits for your reference

No correlation data found on these traits

Overall Test

Data Chi'Square Test Fisher's Exact Test
Number of chrom.:20 χ2=1021.786920
Number of traits:12 df=209
Number of QTLs:94 p-value=3.374971e-107

FOOT NOTE: * : FDR is short for "false discovery rate", representing the expected proportion of type I errors. A type I error is where you incorrectly reject the null hypothesis, i.e. you get a false positive. It's statistical definition is FDR = E(V/R | R > 0) P(R > 0), where V = Number of Type I errors (false positives); R = Number of rejected hypotheses. Benjamini–Hochberg procedure is a practical way to estimate FDR.

 

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