QTL #36567 Description:

 Trait Information
Trait name: Milk osteopontin content Vertebrate Trait Ontology: Milk osteopontin amount
Reported name: Product Trait Ontology: n/a
Symbol: MOPN Clinical Measurement Ontology: n/a
 QTL Map Information
Chromosome:6
QTL Peak Location:38.4 (cM)
QTL Span:13.16-13.36 (cM)
11.9-12.1 (Mbp)
Upper, "Suggestive":n/a
Upper, "Significant":n/a
Peak:
Lower, "Significant":n/a
Lower, "Suggestive":n/a
Analysis type:Association
Model tested:Mendelian
Test base:-
Threshold significance level:Significant
VARIANCEn/a
P_values<0.01
LOD_scoren/a
LS_meann/a
Dominance effect:n/a
Additive effect:n/a
Associated Gene:SPP1 (secreted phosphoprotein 1)
Links:   NCBI GeneDB  |  Edit  |   Map view

 Extended information:
(none)

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  •  QTL Experiment in Brief
    Animals:Animals were Holstein cattle.
     Breeds associated:
    Design:Animals were genotyped for three SNPs in SPP1 and analyzed for milk osteopontin amounts.
    Analysis:The MIXED procedure was used.
    Software:SAS
    Notes: 
    Links:Edit
     Reference
    Authors:Dudemaine P L, Thibault C, Alain K, Bissonnette N
    Affiliation:Département de Biochimie, Faculté de Médecine et des Sciences de la Santé, Université de Sherbrooke, Sherbrooke, QC, J1H 5N4, Canada
    Title:Genetic variations in the SPP1 promoter affect gene expression and the level of osteopontin secretion into bovine milk
    Journal:Animal genetics, 2014, 45(5): 629-40
    Links:  PubMed  |  Abstract   |  List all QTL   |  Edit  

     Additional Information
    Comments:c.-1301G>A/c.-1254C>T;c.-430G>A; total secreted OPN (mg), weeks 25-40
    User inputs on reference #24961487
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