Release 56
(Apr 24, 2025)

This linkage-map based data has been obsolete
(see Release notes 51, 52, 53). Information
provided here is only for retrospective online
support of publications that used this data.

QTL 9830 Description:

 Trait Information
Trait name: C3c concentration Vertebrate Trait Ontology: Complement protein amount
Reported name: C3c concentration Product Trait Ontology: n/a
Symbol: C3C Clinical Measurement Ontology: n/a
 QTL Map Information
Chromosome:14
QTL Peak Location:24 (cM)
QTL Span:10.75-10.77 (cM)
7.2-7.3 (Mbp)
Upper, "Suggestive":n/a
Upper, "Significant":n/a
Peak:
Lower, "Significant":n/a
Lower, "Suggestive":n/a
Marker type:
Analysis type:QTL
Model tested:Mendelian
Test base:Genome-wise
Threshold significance level:Significant
LOD_score3.5
F_Stat8.2
VARIANCE4.0
P_values<0.05
Dominance effect:0.051
Additive effect:0.004
Associated Gene:n/a
Cis/Trans acting type:
Links:   NCBI GeneDB  |  Edit  |   Map view

 Extended information:
(none)

User inputs on QTL #9830
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  •  QTL Experiment in Brief
    Animals:Animals were from a cross between Berlin Miniature pig and Duroc.
     Breeds associated:
    Design:Animals were genotyped for polymorphisms in MBL1 and MBL2 and analyzed for complement activity. Linkage QTL analysis was also performed.
    Analysis:For association analysis, data were analyzed using ANOVA. A least-squares regression model was used for QTL detection.
    Software:SAS, CRIMAP, QTL Express
    Notes: 
    Links:Edit

     Reference
    Authors:Phatsara, C; Jennen, D G J; Ponsuksili, S; Murani, E; Tesfaye, D; Schellander, K; Wimmers, K
    Affiliation:Research Institute for the Biology of Farm Animals (FBN), Research Unit Molecular Biology, 18196 Dummerstorf, Germany; wimmers@fbn-dummerstorf.de
    Title:Molecular genetic analysis of porcine mannose-binding lectin genes, MBL1 and MBL2, and their association with complement activity.
    Journal:International journal of immunogenetics, 2007, 34(1): 55-63
    Links:  PubMed  |  Abstract   |  List all data   |  Edit  

     Additional Information
    Comments:After vaccination with Mycoplasma
    User inputs on reference #17284229
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  • Cite this Data:

    Animal QTLdb: QTL9830 was published in 2007, and was curated into QTLdb on 2009-11-16. DBxREF link to this data: https://www.animalgenome.org/QTLdb/q?id=QTL_ID:9830

     

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