Release 56
(Apr 24, 2025)

QTL 9829 Description:

 Trait Information
Trait name: C3c concentration Vertebrate Trait Ontology: Complement protein amount
Reported name: C3c concentration Product Trait Ontology: n/a
Symbol: C3C Clinical Measurement Ontology: n/a
 QTL Map Information
Chromosome:14
QTL Peak Location:62.78 (cM)
QTL Span:47.1-51 (cM)
83.9-93.4 (Mbp)
Upper, "Suggestive":n/a
Upper, "Significant":SW1536
Peak:
Lower, "Significant":SW1556
Lower, "Suggestive":n/a
Marker type:Microsatellites
Analysis type:Association
Model tested:Mendelian
Test base:n/a
Threshold significance level:Suggestive
P_values0.067
Dominance effect:n/a
Additive effect:n/a
Associated Gene:MBL1 (mannan-binding lectin (A))
Cis/Trans acting type:
Links:   NCBI GeneDB  |  Edit  |   Map view

 Extended information:
(none)

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  •  QTL Experiment in Brief
    Animals:Animals were from a cross between Berlin Miniature pig and Duroc.
     Breeds associated:
    Design:Animals were genotyped for polymorphisms in MBL1 and MBL2 and analyzed for complement activity. Linkage QTL analysis was also performed.
    Analysis:For association analysis, data were analyzed using ANOVA. A least-squares regression model was used for QTL detection.
    Software:SAS, CRIMAP, QTL Express
    Notes: 
    Links:Edit

     Reference
    Authors:Phatsara, C; Jennen, D G J; Ponsuksili, S; Murani, E; Tesfaye, D; Schellander, K; Wimmers, K
    Affiliation:Research Institute for the Biology of Farm Animals (FBN), Research Unit Molecular Biology, 18196 Dummerstorf, Germany; wimmers@fbn-dummerstorf.de
    Title:Molecular genetic analysis of porcine mannose-binding lectin genes, MBL1 and MBL2, and their association with complement activity.
    Journal:International journal of immunogenetics, 2007, 34(1): 55-63
    Links:  PubMed  |  Abstract   |  List all data   |  Edit  
    User inputs on reference #17284229
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  • Cite this Data:

    Animal QTLdb: QTL9829 was published in 2007, and was curated into QTLdb on 2009-11-16. DBxREF link to this data: https://www.animalgenome.org/QTLdb/q?id=QTL_ID:9829

     

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