We constructed a pig F2 resource population by crossing a Meishan sow and aDuroc boar to locate economically important trait loci. The F2 generation wascomposed of 865 animals (450 males and 415 females) from four F1 males and 24 F1females and was genotyped for 180 informative microsatellite markers spanning2,263.6 cM of the whole pig genome. Results of the genome scan showed evidencefor significant quantitative trait loci (<1% genomewise error rate) affectingweight at 30 d and average daily gain on Sus scrofa chromosome (SSC) 6, carcassyield on SSC 7, backfat thickness on SSC 7 and SSC X, vertebra number on SSC 1and SSC 7, loin muscle area on SSC 1 and SSC 7, moisture on SSC 13,intramuscular fat content on SSC 7, and testicular weight on SSC 3 and SSC X.Moreover, 5% genomewise significant QTL were found for birth weight on SSC 7,average daily gain on SSC 4, carcass length on SSC 6, SSC 7, and SSC X andlightness (L value) on SSC 3. We identified 38 QTL for 28 traits at the 5%genomewise level. Of the 38 QTL, 24 QTL for 17 traits were significant at the 1%genomewise level. Analysis of marker genotypes supported the breed of originresults and provided further evidence that a suggestive QTL for circumference ofcannon bone also was segregating within the Meishan parent. We identifiedgenomic regions related with growth and meat quality traits. Fine mapping willbe required for their application in introgression programs and gene cloning.