Release 56
(Apr 24, 2025)

Reference # 12693684 Details:

Authors:Szyda J, Grindflek E, Liu Z, Lien S.
Affiliation:Department of Animal Genetics, Wroclaw Agricultural University, Kozuchowska 7,51-631 Wroclaw, Poland. Contact: szyda@karnet.ar.wroc.pl
Title:Multivariate mixed inheritance models for QTL detection on porcine chromosome 6.
Journal:Genet Res., 2003, 81(1):65-73 DOI: 10.1017/s0016672302006043
Abstract:

A series of multivariate mixed-inheritance models is fitted to the data from anoutbred-line pig cross commercially used in Norway. Each model accommodatesinformation on polygenic (co)variances between F2 individuals and their F1parents across the five traits through incorporation of a random animal effect.Considered traits relate to meat quality and are chosen following up the resultsfrom a previous evaluation, in which a putative quantitative trait locus (QTL)was identified on chromosome six that affects the amount of intramuscular fat(IMF), meat percentage, meat tenderness and smell intensity (Grindflek et al.,2001). An additional trait included in the model, based on results of otherstudies, is the backfat thickness. The analysed material comprises data scoredfor 305 F2 individuals, whereas marker information is available for F1 and F2generations. Based on the results of the multivariate analysis with themixed-inheritance model, it was possible to conclude that the evidence for QTLsfor meat percentage, meat tenderness and smell intensity in the study ofGrindflek et al. (2001) do not represent separate QTLs, but is caused by thefact that the applied pre-adjustment of trait values for polygenic effectsfailed properly to remove the polygenic variation. The QTL effect on IMF onchromosome six was confirmed.

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