Qu YC, Deng CY, Xiong YZ, Zheng R, Yu L, Su YH, Liu GL.
Affiliation:
Key Laboratory of Pig Breeding and Genetics, Agricultural Ministry, HuazhongAgricultural University, Wuhan 430070, China.
Title:
[The construction of the genetic map and QTL locating analysis on chromosome 2in swine]
Journal:
Acta Genetica Sinica, 2002, 29(11):972-6
DOI:
(n/a)
Abstract:
The study constructed the genetic linkage map of porcine chromosome 2 andfurther analysis of quantitative trait loci was conducted. The results of thestudy demonstrated that all 7 microsatellite loci we chose were with relativelyhigh polymorphism, and its polymorphic information content was from 0.40182 to0.58477. The genetic map we constructed for resource family was 152.9 cM inlength, with the order of all loci highly consistent with the USDA map. Allmarker intervals were longer than USDA map with the interval between markerSw2516 and Sw1201 as an exception. Furthermore, we conducted QTLs locatinganalysis by combining the genetic map with the phenotypic data. QTLs affectinglively estimated traits such as lean meat percentage, were located at 60-65 cMon chromosome 2, while QTLs for the height and marbling of Longissmus dorsimuscle were located at 20 cM and 55 cM, respectively Among them, QTL forestimated lean meat percentage was significant at chromosome-wise level (P <0.01) and was responsible for 21.55% of the phenotypic variance. QTLs for theheight and marbling of Longissmus dorsi muscle were responsible for 10.12% and10.97% of the phenotypic variance, respectively. The additive and dominanceeffect of lively estimated traits were in the inverse tendency, while the QTLfor the height of Longissmus dorsi muscle had its additive and dominance effectin the same tendency and was with advantageous allele in Large White. The QTLswe detected had relatively large effect on phenotype and built a basis formolecular marker assisted selection and breeding.