Whole genome analysis for QTL/association enrichment
Running...
Version: Enrich S: beta v0.8
Data:
Number of enzyme activity traits:
3
Number of QTL / associations found:
21
Number of chromosomes where QTL / associations are found:
5
Chi-squared (χ2) test: are enzyme activity traits over-represented on some chromosomes?
Chromosomes
Total χ2
df
p-values
FDR *
Size of χ2
Chromosome X
2.31429
4
0.6781686
6.781686e-01
Chromosome 1
7.31430
4
0.1201822
1.502277e-01
Chromosome 2
7.31430
4
0.1201822
1.502277e-01
Chromosome 7
43.45713
4
8.31718e-09
4.158590e-08
Chromosome 15
7.31430
4
0.1201822
1.502277e-01
Chi-squared (χ2) test: Which of the 3 enzyme activity traits are over-represented in the QTLdb
Traits
Total χ2
df
p-values
FDR *
Size of χ2
Muscle cathepsin B activity
20
2
4.539993e-05
0.0001361998
NADP-malate dehydrogenase activity
5.4
2
0.06720551
0.0672055100
NADPH-generating enzyme activity
5.4
2
0.06720551
0.0672055100
Correlations found between some of these traits for your reference
No correlation data found on these traits
Overall Test
Data
Chi'Square Test
Fisher's Exact Test
Number of chrom.:
5
χ2
=
67.714320
Number of traits:
3
df
=
8
Number of QTLs:
21
p-value
=
1.399067e-11
FOOT NOTE: * : FDR is short for "false
discovery rate", representing the expected proportion of type I errors. A type I
error is where you incorrectly reject the null hypothesis, i.e. you get a false
positive. It's statistical definition is FDR = E(V/R | R > 0) P(R > 0), where
V = Number of Type I errors (false positives); R = Number of rejected hypotheses.
Benjamini–Hochberg procedure is a practical way to estimate FDR.
Running...
