| QTL Map Information |
|---|
| Chromosome: | 2 |
| QTL Peak Location: | 103 (cM) |
| QTL Span: | 94.8-109.2 (cM)
75.3-86.7 (Mbp) |
 |
Upper, "Suggestive": | n/a |
| Upper, "Significant": | FCB128 |
| Peak: | BMS678 |
| Lower, "Significant": | CSAP16E |
| Lower, "Suggestive": | n/a |
| Marker type: | Microsatellites |
| Analysis type: | QTL |
| Model tested: | n/a |
| Test base: | n/a |
| Threshold significance level: | n/a |
 |
LOD_score | 29.5 | | Dominance effect: | n/a |
| Additive effect: | n/a |
| Associated Gene: | TYRP1 (tyrosinase-related protein 1) |
| Cis/Trans acting type: |  |
| Links:
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| Extended information: |
|---|
| (none) |
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| QTL Experiment in Brief |
|---|
| Animals: | 882 free-living Soay sheep (island of Hirta, St Kilda, UK). 571 animals assigned paternity by molecular tests; 663 animals assigned maternity by field observation. Resource flock comprised half-sibships with 12 or more well-phenotyped individuals a |
| Breeds associated:
n/a
|
| Design: | Soay linkage map was developed comprising 247 markers with 15cM intermarker spacing across 3350cM or about 90% of the genome. Related individuals from a free-living population were used. |
| Analysis: | Coat colour and pattern mapping was performed assuming a single bi-allelic locus for each trait. Following a whole genome scan for the horns locus, target regions were subject to parametric multipoint analysis. Marker allele frequencies were estimated b |
| Software: | CRI-MAP, Linkage, Loki |
| Notes: | LOD threshold for linkage set at 3.3 as per Lander and Kruglyak (Nature Genetics, 11:241-247, 19 |
| Links: | Edit |
| Reference |
|---|
| Authors: | Beraldi D, McRae AF, Gratten J, Slate J, Visscher PM, Pemberton JM |
| Affiliation: | Institute of Evolutionary Biology, School of Biological Sciences, University of Edinburgh, Edinburgh, UK |
| Title: | Development of a linkage map and mapping of phenotypic polymorphisms in a free-living population of Soay sheep (Ovis aries) |
| Journal: | Genetics, 2006, 173:1521-1537 |
| Links: |
PubMed | Abstract | List all data
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| Additional Information |
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| Comments: | PMID 17254985: LOD 110.20 (p<0.0001) for an association between coat colour and a mutation in TYRP1 in these Soay::Ref_map: IMF4 |
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