QTL Map Information |
Chromosome: | 4 |
QTL Peak Location: | 428.19 (cM) |
QTL Span: | 428.19-428.19 (cM) 77.3-77.3 (Mbp) |
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Upper, "Suggestive": | n/a |
Upper, "Significant": | n/a |
Peak: | rs69587062 |
Lower, "Significant": | n/a |
Lower, "Suggestive": | n/a |
Marker type: | SNP |
Analysis type: | Association |
Model tested: | Mendelian |
Test base: | Comparison-wise |
Threshold significance level: | Significant |
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P_values | 4.28E-5 | Dominance effect: | n/a |
Additive effect: | n/a |
Associated Gene: | n/a |
Cis/Trans acting type: |  |
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Extended information: |
(none) |
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QTL Experiment in Brief |
Animals: | Animals were Thoroughbred stallions. |
Breeds associated:
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Design: | Animals were genotyped using the Illumina Equine SNP50 BeadChip and analyzed for impaired acrosome reaction. A total of 41521 SNPs were used for analysis. SNPs in candidate genes were selected for further genotyping. |
Analysis: | Chi-square and Fisher's exact tests were used. |
Software: | MTDFREML, PLINK, R software, Haploview |
Notes: | |
Links: | Edit |
Reference |
Authors: | Raudsepp T, McCue ME, Das Pranab J, Dobson L, Vishnoi M, Fritz KL, Schaefer R, Rendahl AK, Derr JN, Love CC, Varner DD, Chowdhary BP |
Affiliation: | Department of Veterinary Integrative Biosciences, Texas A&M University, College Station, Texas, USA |
Title: | Genome-wide association study implicates testis-sperm specific FKBP6 as a susceptibility locus for impaired acrosome reaction in stallions |
Journal: | PLoS genetics, 2012, 8(12): e1003139 |
Links: |
PubMed | Abstract | List all data
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Additional Information |
Comments: | Impaired acrosome reaction |

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