| QTL Map Information |
|---|
| Chromosome: | 1 |
| QTL Peak Location: | n/a |
| QTL Span: | n/a
|
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Upper, "Suggestive": | n/a |
| Upper, "Significant": | rs3423115783 |
| Peak: | |
| Lower, "Significant": | rs109498562 |
| Lower, "Suggestive": | n/a |
| Marker type: | Haplotype |
| Analysis type: | QTL |
| Model tested: | - |
| Test base: | Genome-wise |
| Threshold significance level: | Significant |
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P_values | <0.05 | | Dominance effect: | n/a |
| Additive effect: | n/a |
| Associated Gene: | n/a |
| Cis/Trans acting type: |  |
| Links:
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| Extended information: |
|---|
| (none) |
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| QTL Experiment in Brief |
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| Animals: | Animals were Brown Swiss bulls. |
| Breeds associated:
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| Design: | Animals were gentoyped using Illumina BovineSNP BeadChips containing between 20K and 777K SNPs. Lower-density data were imputed to 777K and haplotype-based association testing was performed for bull fertility traits. A total of 683,609 SNPs were used for analysis. Fine mapping was carried out using whole-genome sequencing data. |
| Analysis: | Association testing was performed using a sliding window-based approach with a linear model. |
| Software: | Beagle 5.1, GCTA v1.93.2, R software, PLINK v1.9, GATK, Burrows Wheeler Aligner |
| Notes: | |
| Links: | Edit |
| Reference |
|---|
| Authors: | Hiltpold M, Kadri NK, Janett F, Witschi U, Schmitz-Hsu F, Pausch H |
| Affiliation: | Animal Genomics, Institute of Agricultural Sciences, ETH Zürich, Eschikon 27, 8315, Lindau, Switzerland |
| Title: | Autosomal recessive loci contribute significantly to quantitative variation of male fertility in a dairy cattle population |
| Journal: | BMC Genomics, 2021, 22(1): 225 |
| Links: |
PubMed | Abstract | List all data
| Edit |
| Additional Information |
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| Comments: | Recessive mode of inheritance |
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