Release 56
(Apr 24, 2025)

QTL 224117 Description:

 Trait Information
Trait name: Bilateral convergent strabismus with exophthalmus Vertebrate Trait Ontology: Eye morphology trait
Reported name: (n/a) Product Trait Ontology: n/a
Symbol: BCSE Clinical Measurement Ontology: n/a
 QTL Map Information
Chromosome:12
QTL Peak Location:n/a
QTL Span:n/a
Upper, "Suggestive":n/a
Upper, "Significant":n/a
Peak:rs110347081
Lower, "Significant":n/a
Lower, "Suggestive":n/a
Marker type:SNP
Analysis type:Association
Model tested:n/a
Test base:Genome-wise
Threshold significance level:Significant
P_values<0.05
Dominance effect:n/a
Additive effect:n/a
Associated Gene:LOC100337390 (multidrug resistance-associated protein 4-like)
Cis/Trans acting type:
Links:   Edit  |   Map view

 Extended information:
(none)

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  •  QTL Experiment in Brief
    Animals:Animals were German and Swiss Holstein cows.
     Breeds associated:
    Design:Animals were genotyped using the Illumina BovineHD BeadChip, with data imputed to sequence level, and GWAS was performed for bilateral convergent strabismus with exophthalmos. A total of 10,772,372 SNPs were used for analysis.
    Analysis:Logistic regression was used for single-marker GWAS.
    Software:PLINK 1.9, Beagle 5.0
    Notes: 
    Links:Edit

     Reference
    Authors:Bögeholz A, Falker-Gieske C, Guélat M, Gurtner C, Hunziker S, Oevermann A, Thaller G, Drögemüller C, Tetens J
    Affiliation:Department of Animal Sciences, Georg-August-University Göttingen, Burckhardtweg 2, 37077 Göttingen, Germany
    Title:GWAS Hits for Bilateral Convergent Strabismus with Exophthalmos in Holstein Cattle Using Imputed Sequence Level Genotypes.
    Journal:Genes, 2021, 12(7):1039
    Links:  PubMed  |  Abstract   |  List all data   |  Edit  
    User inputs on reference #34356055
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  • Cite this Data:

    Animal QTLdb: QTL224117 was published in 2021, and was curated into QTLdb on 2021-08-19. DBxREF link to this data: https://www.animalgenome.org/QTLdb/q?id=QTL_ID:224117

     

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