| QTL Map Information |
|---|
| Chromosome: | 7 |
| QTL Peak Location: | n/a |
| QTL Span: | n/a
|
 |
Upper, "Suggestive": | n/a |
| Upper, "Significant": | n/a |
| Peak: | rs109237111 |
| Lower, "Significant": | n/a |
| Lower, "Suggestive": | n/a |
| Marker type: | SNP |
| Analysis type: | eQTL |
| Model tested: | n/a |
| Test base: | Experiment-wise |
| Threshold significance level: | Significant |
 |
FDR | 8.52E-06 | | Dominance effect: | n/a |
| Additive effect: | n/a |
| Associated Gene: | ACER1 (alkaline ceramidase 1) |
| Cis/Trans acting type: | Cis  |
| Links:
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| Extended information: |
|---|
| (none) |
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| QTL Experiment in Brief |
|---|
| Animals: | Animals were Holstein Friesian cattle. |
| Breeds associated:
n/a
|
| Design: | Animals were genotyped using the Illumina LD EuroG10K BeadChip and eQTL were identified. A case-control study was performed to investigate the association of eQTL SNPs and MAP infection. |
| Analysis: | For the case-control study, logistic regression models were used. Linear regression analysis was used for cis-eQTL discovery. |
| Software: | R Matrix eQTL 2.2, SNPassoc 1.9.2 |
| Notes: | |
| Links: | Edit |
| Reference |
|---|
| Authors: | Canive M, Fernandez-Jimenez N, Casais R, Vázquez P, Lavín JL, Bilbao JR, Blanco-Vázquez C, Garrido JM, Juste RA, Alonso-Hearn M |
| Affiliation: | Department of Animal Health, NEIKER- Basque Research and Technology Alliance (BRTA), Derio, Bizkaia, Spain |
| Title: | Identification of loci associated with susceptibility to bovine paratuberculosis and with the dysregulation of the MECOM, eEF1A2, and U1 spliceosomal RNA expression |
| Journal: | Scientific reports, 2021, 11(1): 313 |
| Links: |
PubMed | Abstract | List all data
| Edit |
| Additional Information |
|---|
| Comments: | peripheral blood |
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