Release 56
(Apr 24, 2025)

QTL 21158 Description:

 Trait Information
Trait name: Eye area pigmentation Vertebrate Trait Ontology: Skin pigmentation trait
Reported name: Eye area pigmentation Product Trait Ontology: n/a
Symbol: EYEAP Clinical Measurement Ontology: n/a
 QTL Map Information
Chromosome:22
QTL Peak Location:50.50 (cM)
QTL Span:50.50-50.50 (cM)
32.1-32.1 (Mbp)
Upper, "Suggestive":n/a
Upper, "Significant":n/a
Peak:rs137749800
Lower, "Significant":n/a
Lower, "Suggestive":n/a
Marker type:SNP
Analysis type:Association
Model tested:Mendelian
Test base:Comparison-wise
Threshold significance level:Significant
P_values3.75E-26
Dominance effect:n/a
Additive effect:n/a
Associated Gene:MITF (microphthalmia-associated transcription factor)
Cis/Trans acting type:
Links:   NCBI GeneDB  |  Edit  |   Map view

 Extended information:
(none)

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  •  QTL Experiment in Brief
    Animals:Animals were Fleckvieh cattle.
     Breeds associated:
    Design:Animals were genotyped using three SNP arrays, with a resulting dataset comprising 658385 SNPs, and analyzed for eye-area pigmentation.
    Analysis:A variance component-based approach was used.
    Software:EMMAX, PLINK
    Notes: 
    Links:Edit

     Reference
    Authors:Pausch H, Wang X, Jung S, Krogmeier D, Edel C, Emmerling R, Götz KU, Fries R
    Affiliation:Lehrstuhl fuer Tierzucht, Technische Universitaet Muenchen, Freising, Germany.
    Title:Identification of QTL for UV-protective eye area pigmentation in cattle by progeny phenotyping and genome-wide association analysis.
    Journal:PloS one, 2012, 7 (5): e36346
    Links:  PubMed  |  Abstract   |  List all data   |  Edit  
    User inputs on reference #22567150
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  • Cite this Data:

    Animal QTLdb: QTL21158 was published in 2012, and was curated into QTLdb on 2013-05-30. DBxREF link to this data: https://www.animalgenome.org/QTLdb/q?id=QTL_ID:21158

     

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