Release 56
(Apr 24, 2025)

QTL 165374 Description:

 Trait Information
Trait name: Immunoglobulin G level Vertebrate Trait Ontology: Blood immunoglobulin G amount
Reported name: (n/a) Product Trait Ontology: n/a
Symbol: SIGG Clinical Measurement Ontology: Blood immunoglobulin G level
 QTL Map Information
Chromosome:21
QTL Peak Location:85.51 (cM)
QTL Span:85.51-85.51 (cM)
68.5-68.5 (Mbp)
Upper, "Suggestive":n/a
Upper, "Significant":n/a
Peak:rs111018334
Lower, "Significant":n/a
Lower, "Suggestive":n/a
Marker type:SNP
Analysis type:Association
Model tested:Mendelian
Test base:Experiment-wise
Threshold significance level:Significant
P_values9.13E-4
Dominance effect:n/a
Additive effect:n/a
Associated Gene:n/a
Cis/Trans acting type:
Links:   Edit  |   Map view

 Extended information:
(none)

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  •  QTL Experiment in Brief
    Animals:Animals were Canadian Holstein cattle.
     Breeds associated:
    Design:Animals were genotyped using the Illumina BovineSNP50 BeadChip and analyzed for natural antibody level (IgG and IgM). A total of 43,471 SNPs were used for analysis.
    Analysis:A univariate linear mixed model was used.
    Software:FIimpute, snp1101
    Notes: 
    Links:Edit

     Reference
    Authors:de Klerk B, Emam M, Thompson-Crispi KA, Sargolzaei M, van der Poel JJ, Mallard BA
    Affiliation:Department of Pathobiology, Ontario Veterinary College, Genetic improvement of livestock, University of Guelph, Guelph, ON, N1G 2W1, Canada
    Title:A genome-wide association study for natural antibodies measured in blood of Canadian Holstein cows
    Journal:BMC genomics, 2018, 19(1): 694
    Links:  PubMed  |  Abstract   |  List all data   |  Edit  
    User inputs on reference #30241501
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  • Cite this Data:

    Animal QTLdb: QTL165374 was published in 2018, and was curated into QTLdb on 2018-11-27. DBxREF link to this data: https://www.animalgenome.org/QTLdb/q?id=QTL_ID:165374

     

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