QTL #160384 Description:

 Trait Information
Trait name: Bovine respiratory disease susceptibility Vertebrate Trait Ontology: n/a
Reported name: Product Trait Ontology: n/a
Symbol: BRDS Clinical Measurement Ontology: Disease process measurement
 QTL Map Information
Chromosome:28
QTL Peak Location:46.44 (cM)
QTL Span:46.44-46.44 (cM)
32.9-32.9 (Mbp)
Upper, "Suggestive":n/a
Upper, "Significant":n/a
Peak:rs137709066
Lower, "Significant":n/a
Lower, "Suggestive":n/a
Analysis type:Association
Model tested:-
Test base:-
Threshold significance level:-
VARIANCEn/a
P_values0.0334
LOD_scoren/a
LS_meann/a
Dominance effect:n/a
Additive effect:n/a
Associated Gene: ()
Links:   Edit  |   Map view
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  •  QTL Experiment in Brief
    Animals:The data set consisted of 2,762 Holstein calves, 1,323 Angus,85 Red Angus, 66 Hereford, 118 Charolais, and 408 crossbred beef cattle.
     Breeds associated:
    Design:Animals were genotyped using the BovineHD BeadChip and suceptibility to bovine respiratory disease. A marker was selected as a proxy for each gene within the bovine genome. The final analysis included markers as proxies for 19,723 genes within 3,147 gene sets.
    Analysis:Gene-set enrhciment anlaysis utilitzing SNP data was used. Dairy and beef cattle were analyzed seperately. Individual dairy populations (California and New Mexico) were analyzed both sperately and jointly, while individual beef populations (Colorado and Washington) were analyzed seperately.
    Software:Golden Helix SNP and Variation Suite (SVS), R - GenAbel
    Notes:This study used some data that were previously analyzed (PMID 25534905).
    Links:Edit
     Reference
    Authors:Neupane M, Kiser JN, the Bovine Respiratory Disease Complex Coordinated Agricultural Project Research Team, Neibergs HL
    Affiliation:Department of Animal Sciences, Washington State University, Pullman WA 99164; Department of Veterinary Pathobiology, College of Veterinary Medicine, Texas A&M University, College Station TX 77843
    Title:Gene set enrichment analysis of SNP data in dairy and beef cattle with bovine respiratory disease.
    Journal:Animal Genetics, 2018, 49(6):527-538
    Links:  PubMed  |  Abstract   |  List all QTL   |  Edit  

     Additional Information
    Comments:Proxy for KCNMA1 in the Combined Beef data
    User inputs on reference #30229962
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