QTL #106138 Description:

 Trait Information
Trait name: Bovine tuberculosis susceptibility Vertebrate Trait Ontology: n/a
Reported name: Product Trait Ontology: n/a
Symbol: BTBS Clinical Measurement Ontology: Disease process measurement
 QTL Map Information
Chromosome:18
QTL Peak Location:24.6 (cM)
QTL Span:23.66-23.86 (cM)
18.1-18.2 (Mbp)
Upper, "Suggestive":n/a
Upper, "Significant":n/a
Peak:
Lower, "Significant":n/a
Lower, "Suggestive":n/a
Analysis type:Association
Model tested:Mendelian
Test base:-
Threshold significance level:Significant
VARIANCEn/a
P_values0.0001
LOD_scoren/a
LS_meann/a
Dominance effect:n/a
Additive effect:n/a
Associated Gene:NOD2 (nucleotide-binding oligomerization domain containing 2)
Links:   Edit  |   Map view

 Extended information:
(none)

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  •  QTL Experiment in Brief
    Animals:Animals were Chinese Holstein cows.
     Breeds associated:
    Design:Animals were genotyped for five SNPs in CARD15 (NOD2) and analyzed for susceptibility to bovine tuberculosis.
    Analysis:Allele and genotype frequencies were compared between cases and controls using chi-square or Fisher's exact test.
    Software:SPSS, SHEsis
    Notes: 
    Links:Edit
     Reference
    Authors:Wang Y, Wang S, Liu T, Tu W, Li W, Dong G, Xu C, Qin B, Liu K, Yang J, Chai J, Shi X, Zhang Y
    Affiliation:College of Animal Science and Technology, Yunnan Agricultural University, Kunming, Yunnan Province, China
    Title:CARD15 Gene Polymorphisms Are Associated with Tuberculosis Susceptibility in Chinese Holstein Cows
    Journal:PloS one, 2015, 10(8): e0135085
    Links:  PubMed  |  Abstract   |  List all QTL   |  Edit  

     Additional Information
    Comments:SNP E4 (-37)
    User inputs on reference #26244859
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