QTLdb: entrichment tests

Release 56
(Apr 24, 2025)

Whole genome analysis for QTL/association enrichment

Running...

Version: Enrich S: beta v0.8

Search:	to limit the list of your trait choices:
	(optional) focus on chromosome with Mb windows across its length

Data:

Number of general health parameters traits:	5
Number of QTL / associations found:	110
Number of chromosomes where QTL / associations are found:	30

Chi-squared (χ²) test: are general health parameters traits over-represented on some chromosomes?

Chromosomes	Total χ²	df	p-values	FDR ^*	Size of χ²
Chromosome X	0.60605	29	0.998329325823115	9.999827e-01
Chromosome 1	3.78790	29	0.998329325823115	9.999827e-01
Chromosome 2	9.69695	29	0.9997057	9.999827e-01
Chromosome 3	242.42425	29	1.49085e-35	4.472550e-34
Chromosome 4	0.60605	29	0.998329325823115	9.999827e-01
Chromosome 5	7.42425	29	0.9999827	9.999827e-01
Chromosome 6	15.15150	29	0.9837983	9.999827e-01
Chromosome 7	3.78790	29	0.998329325823115	9.999827e-01
Chromosome 8	0.15150	29	0.998329325823115	9.999827e-01
Chromosome 9	0.60605	29	0.998329325823115	9.999827e-01
Chromosome 10	3.78790	29	0.998329325823115	9.999827e-01
Chromosome 11	3.78790	29	0.998329325823115	9.999827e-01
Chromosome 12	0.60605	29	0.998329325823115	9.999827e-01
Chromosome 13	0.60605	29	0.998329325823115	9.999827e-01
Chromosome 14	15.15150	29	0.9837983	9.999827e-01
Chromosome 15	3.78790	29	0.998329325823115	9.999827e-01
Chromosome 16	3.78790	29	0.998329325823115	9.999827e-01
Chromosome 17	9.69695	29	0.9997057	9.999827e-01
Chromosome 18	3.78790	29	0.998329325823115	9.999827e-01
Chromosome 19	9.69695	29	0.9997057	9.999827e-01
Chromosome 20	3.78790	29	0.998329325823115	9.999827e-01
Chromosome 21	9.69695	29	0.9997057	9.999827e-01
Chromosome 22	0.60605	29	0.998329325823115	9.999827e-01
Chromosome 23	118.78790	29	7.887552e-13	1.183133e-11
Chromosome 24	0.60605	29	0.998329325823115	9.999827e-01
Chromosome 25	7.42425	29	0.9999827	9.999827e-01
Chromosome 26	2.42425	29	0.998329325823115	9.999827e-01
Chromosome 27	9.69695	29	0.9997057	9.999827e-01
Chromosome 28	9.69695	29	0.9997057	9.999827e-01
Chromosome 29	3.78790	29	0.998329325823115	9.999827e-01

Chi-squared (χ²) test: Which of the 5 general health parameters traits are over-represented in the QTLdb

Traits	Total χ²	df	p-values	FDR ^*	Size of χ²
Body temperature	18.04724	4	0.001208137	1.510171e-03
Cold tolerance	54.69229	4	3.768896e-11	1.884448e-10
General health index	14.71425	4	0.005332098	5.332098e-03
Heat tolerance	27.8378	4	1.345350e-05	3.363375e-05
Respiratory rate	21.62284	4	0.0002382111	3.970185e-04

Correlations found between some of these traits for your reference

No correlation data found on these traits

Overall Test

Data		Chi'Square Test			Fisher's Exact Test
Number of chrom.:	30	χ²	=	505.454550
Number of traits:	5	df	=	116
Number of QTLs:	110	p-value	=	4.96283e-50

FOOT NOTE: * : FDR is short for "false discovery rate", representing the expected proportion of type I errors. A type I error is where you incorrectly reject the null hypothesis, i.e. you get a false positive. It's statistical definition is FDR = E(V/R | R > 0) P(R > 0), where V = Number of Type I errors (false positives); R = Number of rejected hypotheses. Benjamini–Hochberg procedure is a practical way to estimate FDR.